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Age estimates
Biological age is the most marketable number in consumer health and one of the least stable. We cover what the clocks measure, how much they wobble, and what the researchers who build them say about consumer use.
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Biological ageA 2026 reliability study found that DNA methylation clocks are highly reproducible in the lab and considerably less stable in the person. That distinction matters enormously.
Biological ageMethylation clocks, telomere length, blood biomarker algorithms, glycan analysis, and composite scores measure different things. Disagreement between them is expected, not anomalous.
Biological ageCohort data points at the same short list every time, and none of it is available in a bottle.
Biological ageThe absence is not an oversight. Guidelines require a demonstrated change in management, and that demonstration has not been made.
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